Three steps to use ARTEMIS:

• Input the corresponding values for demographic and clinical biomarkers (Age, Pathologic T, Lymph node status, Pathologic M, ER);
• Click "Edit score" to input the corresponding values for epigenetic biomarkers;
• Wait a few seconds, then see the predictions in the interactive KM plot.

Data sources:

• TCGA cohort: https://xenabrowser.net/
• GEO cohorts: https://www.ncbi.nlm.nih.gov/geo/

If you use ARTEMIS in your work, please cite:

• Maojie Xue#, Ziang Xu#, Xiang Wang#, Jiajin Chen, Xinxin Kong, Shenxuan Zhou, Jiamin Wu, Yuhao Zhang, Yi Li, David C. Christiani, Feng Chen*, Yang Zhao*, Ruyang Zhang*. ARTEMIS: an independently validated prognostic prediction model of breast cancer incorporating epigenetic biomarkers with main effects and gene-gene interactions. Journal of Advanced Research. 2024. In Press.

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