Three steps to use APOLLO:

• Input the corresponding values for demographic and clinical biomarkers (Age, Grade, IDH and 1p/19q);
• Click ‘Edit score’ to input the corresponding values for transcriptional biomarkers;
• Wait a few seconds, then see the predictions in the interactive KM plot.

Data sources:

• CGGA cohort: http://www.cgga.org.cn/
• TCGA cohort: https://xenabrowser.net/
• GEO cohorts: https://www.ncbi.nlm.nih.gov/geo/

If you use APOLLO in your work, please cite:

• Jiajin Chen†, Sipeng Shen†, Yi Li†, Juanjuan Fan†, Shiyu Xiong, Jingtong Xu, Chenxu Zhu, Lijuan Lin, Xuesi Dong, Weiwei Duan, Yang Zhao, Xu Qian, Zhonghua Liu, Yongyue Wei, David C. Christiani*, Ruyang Zhang*, Feng Chen*. APOLLO: an accurate and independently validated prediction model of lower-grade gliomas overall survival and a comparative study of model performance. eBioMedicine. 2022;79:104007

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